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Tirzepatide as Compared with Semaglutide for the Treatment of Obesity @NEJM Among participants with obesity but without diabetes, treatment with tirzepatide was superior to treatment with semaglutide with respect to reduction in

GLP-1 medications like semaglutide (Ozempic) and tirzepatide (Mounjaro) have traditionally been used to treat diabetes. They work by mimicking a natural hormone called GLP-1, which helps regulate blood sugar levels and appetite.

SURMOUNT-3: Tirzepatide shows total mean weight loss of 26.6% from study entry over 84 weeks

Weight-loss drugs could see a shortage until 2025, makers predict

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