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In the phase 3 ACHIEVE-1 trial, published in June 2025, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with
Editor's Choice: Exercise Boosts GLP-1 Response After Weight Loss New research reveals that 1 year of moderate-to-vigorous exercise after diet-induced weight loss can significantly increase late-phase postprandial GLP-1 secretiona key hormone
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